MOV10L1 antibody (AA 336-425)

Catalog No. ABIN7168291

This anti-MOV10L1 antibody is a Rabbit Polyclonal antibody detecting MOV10L1 in WB, ELISA, IHC and IF. Suitable for Human.

Quick Overview for MOV10L1 antibody (AA 336-425) (ABIN7168291)

Target: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOV10L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MOV10L1 Antibody

Binding Specificity: AA 336-425

Purpose: MOV10L1 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human RNA helicase Mov10l1 protein (336-425AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MOV10L1

Target: MOV10L1 (Mov10l1, Moloney Leukemia Virus 10-Like 1 (MOV10L1))

Alternative Name: MOV10L1

Background:

Background: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5\\\'-3\\\' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.

Aliases: Cardiac helicase activated by MEF2 protein antibody, Cardiac specific RNA helicase antibody, CHAMP antibody, Csm antibody, M10L1_HUMAN antibody, Moloney leukemia virus 10 like protein 1 antibody, Moloney leukemia virus 10-like protein 1 antibody, MOV10 like 1 antibody, MOV10 like protein 1 antibody, MOV10-like protein 1 antibody, MOV10L1 antibody, Mov10l1, Moloney leukemia virus 10 like 1, homolog (mouse) antibody, Putative helicase Mov10l1 antibody

UniProt: Q9BXT6