RRM1 antibody

Catalog No. ABIN7168449

The Mouse Monoclonal anti-RRM1 antibody is suitable to detect RRM1 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for RRM1 antibody (ABIN7168449)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 3D6H5

Product Details anti-RRM1 Antibody

Purpose: RRM1 Monoclonal Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human RRM1 Protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: RRM1

Background:

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Aliases: Ribonucleotide Reductase M1,RRM1,RR1

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity