DVL2 antibody (AA 1-240)

Catalog No. ABIN7168752

The Rabbit Polyclonal anti-DVL2 antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect DVL2 in samples from Human.

Quick Overview for DVL2 antibody (AA 1-240) (ABIN7168752)

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-DVL2 Antibody

Binding Specificity: AA 1-240

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Segment polarity protein dishevelled homolog DVL-2 protein (1-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Alternative Name: DVL2

Background:

Background: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes .

Aliases: Dishevelled 2 (homologous to Drosophila dsh) antibody, Dishevelled dsh homolog 2 antibody, dishevelled segment polarity protein 2 antibody, Dishevelled-2 antibody, Dishevelled2 antibody, DSH homolog 2 antibody, DVL 2 antibody, Dvl2 antibody, DVL2_HUMAN antibody, Segment polarity protein dishevelled homolog DVL 2 antibody, Segment polarity protein dishevelled homolog DVL-2 antibody, Segment polarity protein dishevelled homolog DVL2 antibody

UniProt: O14641

Pathways: Tube Formation