Septin 2 antibody (AA 1-361) (FITC)

Catalog No. ABIN7168867

This anti-Septin 2 antibody is a Rabbit Polyclonal antibody detecting Septin 2 in . Suitable for Human.

Quick Overview for Septin 2 antibody (AA 1-361) (FITC) (ABIN7168867)

Target: Septin 2 (SEPT2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 2 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-Septin 2 Antibody (FITC)

Binding Specificity: AA 1-361

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Septin-2 protein (1-361AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Septin 2

Target: Septin 2 (SEPT2)

Alternative Name: SEPT2

Background:

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Aliases: SEPTIN2 antibody, DIFF6 antibody, KIAA0158 antibody, NEDD5 antibody, SEPT2 antibody, Septin-2 antibody, Neural precursor cell expressed developmentally down-regulated protein 5 antibody, NEDD-5 antibody

UniProt: Q15019