SRGN antibody (AA 28-154)

Catalog No. ABIN7168875

The Rabbit Polyclonal anti-SRGN antibody has been validated for IHC and ELISA. It is suitable to detect SRGN in samples from Human.

Quick Overview for SRGN antibody (AA 28-154) (ABIN7168875)

Target: SRGN (serglycin (SRGN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SRGN Antibody

Binding Specificity: AA 28-154

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serglycin protein (28-154AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN

Background:

Background: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Aliases: Chondroitin sulfate proteoglycan core protein antibody, Cytolytic granule proteoglycan core protein antibody, FLJ12930 antibody, gp600 antibody, Hematopoetic proteoglycan core protein antibody, Mastocytoma proteoglycan core protein antibody, MGC9289 antibody, OTTHUMP00000019716 antibody, P.PG antibody, PG19 core protein antibody, Pgsg antibody, Platelet proteoglycan core protein antibody, platelet proteoglycan protein core antibody, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG antibody, PPG antibody, PRG antibody, PRG1 antibody, PROTEOGLYCAN 1 antibody, proteoglycan 1, secretory granule antibody, Proteoglycan 10K core protein antibody, Proteoglycan peptide core protein antibody, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE antibody, secretory granule proteoglycan 1 antibody, Secretory granule proteoglycan core peptide antibody, Secretory granule proteoglycan core protein antibody, Serglycin antibody, serglycin proteoglycan antibody, Sgc antibody, Srgn antibody, SRGN_HUMAN antibody

UniProt: P10124

Pathways: Maintenance of Protein Location