ICK antibody (AA 150-275)

Catalog No. ABIN7169051

This Rabbit Polyclonal antibody specifically detects ICK in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for ICK antibody (AA 150-275) (ABIN7169051)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ICK Antibody

Binding Specificity: AA 150-275

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: ICK

Background:

Background: Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).

Aliases: CILK1 antibody, ICK antibody, KIAA0936Serine/threonine-protein kinase ICK antibody, EC 2.7.11.1 antibody, Ciliogenesis associated kinase 1 antibody, Intestinal cell kinase antibody, hICK antibody, Laryngeal cancer kinase 2 antibody, LCK2 antibody, MAK-related kinase antibody, MRK antibody

UniProt: Q9UPZ9