PAK6 antibody (AA 1-270)
Quick Overview for PAK6 antibody (AA 1-270) (ABIN7169136)
Target
See all PAK6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-270
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Serine/threonine-protein kinase PAK 6 protein (1-270AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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Alternative Name
- PAK6
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Background
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Background: Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
Aliases: CDKN1A activated kinase 6 antibody, EC 2.7.1.37 antibody, p21 activated protein kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody, p21(CDKN1A) activated kinase 6 antibody, p21-activated kinase 6 antibody, p21activated kinase 6 antibody, PAK 5 antibody, PAK 6 antibody, PAK-5 antibody, PAK-6 antibody, PAK5 antibody, Pak6 antibody, PAK6_HUMAN antibody, Serine threonine protein kinase PAK 6 antibody, Serine/threonine protein kinase PAK 6 antibody, Serine/threonine protein kinase PAK6 antibody, Serine/threonine-protein kinase PAK 6 antibody
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UniProt
- Q9NQU5
Target
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