SMO antibody (AA 28-233)

Catalog No. ABIN7169898

The Rabbit Polyclonal anti-SMO antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect SMO in samples from Human.

Quick Overview for SMO antibody (AA 28-233) (ABIN7169898)

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SMO Antibody

Binding Specificity: AA 28-233

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Smoothened homolog protein (28-233AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMO

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Alternative Name: SMO

Background:

Background: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.

Aliases: Frizzled family member 11 antibody, FZD11 antibody, Gx antibody, Gx protein antibody, Protein Gx antibody, SMO antibody, SMO_HUMAN antibody, SMOH antibody, Smoothened frizzled family receptor antibody, Smoothened homolog (Drosophila) antibody, Smoothened homolog antibody, Smoothened homolog precursor (SMO) (Gx protein) antibody, Smoothened seven transmembrane spanning receptor antibody

UniProt: Q99835

Pathways: Hedgehog Signaling