SLC25A33 antibody (AA 66-120) (HRP)

Catalog No. ABIN7170186

The Rabbit Polyclonal anti-SLC25A33 antibody has been validated for ELISA. It is suitable to detect SLC25A33 in samples from Human.

Quick Overview for SLC25A33 antibody (AA 66-120) (HRP) (ABIN7170186)

Target: SLC25A33 (Solute Carrier Family 25, Member 33 (SLC25A33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A33 antibody is conjugated to HRP

Application: ELISA

Product Details anti-SLC25A33 Antibody (HRP)

Binding Specificity: AA 66-120

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Solute carrier family 25 member 33 protein (66-120AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC25A33

Target: SLC25A33 (Solute Carrier Family 25, Member 33 (SLC25A33))

Alternative Name: SLC25A33

Background:

Background: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is inhibited strongly by pyridoxal 5\'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PubMed:14715278).

Aliases: BMSC MCP antibody, BMSC-MCP antibody, Bone marrow stromal cell mitochondrial carrier protein antibody, HuBMSC MCP antibody, HuBMSC-MCP antibody, MGC4399 antibody, Mitochondrial carrier protein antibody, Novel mitochondrial carrier protein antibody, PNC1 protein antibody, Protein PNC1 antibody, S2533_HUMAN antibody, Slc25a33 antibody, Solute carrier family 25 member 33 antibody

UniProt: Q9BSK2