SOS1 antibody (AA 1140-1281)

Catalog No. ABIN7170318

The Rabbit Polyclonal anti-SOS1 antibody has been validated for WB, ELISA, IF and IHC. It is suitable to detect SOS1 in samples from Human.

Quick Overview for SOS1 antibody (AA 1140-1281) (ABIN7170318)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-SOS1 Antibody

Binding Specificity: AA 1140-1281

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Son of sevenless homolog 1 protein (1140-1281AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1

Background:

Background: Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).

Aliases: alternate SOS1 antibody, GF1 antibody, GGF1 antibody, GINGF antibody, gingival fibromatosis antibody, gingival fibromatosis hereditary 1 antibody, Guanine nucleotide exchange factor antibody, HGF antibody, NS4 antibody, Son of sevenless homolog 1 (Drosophila) antibody, Son of sevenless homolog 1 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, SOS-1 antibody, Sos1 antibody, SOS1_HUMAN antibody

UniProt: Q07889

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling