ESRRA antibody (AA 1-423)

Catalog No. ABIN7170761

This Rabbit Polyclonal antibody specifically detects ESRRA in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for ESRRA antibody (AA 1-423) (ABIN7170761)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-ESRRA Antibody

Binding Specificity: AA 1-423

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Steroid hormone receptor ERR1 protein (1-423AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: ESRRA

Background:

Background: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5\\\'-TNAAGGTCA-3\\\'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Aliases: Err 1 antibody, ERR a antibody, ERR alpha antibody, ERR-alpha antibody, Err1 antibody, ERR1 protein antibody, ERR1_HUMAN antibody, ERRa antibody, ERRalpha antibody, ESRL 1 antibody, ESRL1 antibody, ESRR A antibody, Esrra antibody, Estrogen receptor like 1 antibody, Estrogen receptor related 1 antibody, estrogen receptor related receptor alpha antibody, Estrogen receptor-like 1 antibody, Estrogen related receptor alpha antibody, Estrogen-related receptor alpha antibody, Estrra antibody, hERR1 antibody, NR3B1 antibody, Nuclear receptor subfamily 3 group B member 1 antibody, Steroid hormone receptor ERR1 antibody

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha