ST5 antibody (AA 3-280)

Catalog No. ABIN7170987

The Rabbit Polyclonal anti-ST5 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ST5 in samples from Human.

Quick Overview for ST5 antibody (AA 3-280) (ABIN7170987)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ST5 Antibody

Binding Specificity: AA 3-280

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Suppression of tumorigenicity 5 protein (3-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5

Background:

Background: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Aliases: DENND2B antibody, DENN domain containing protein 2B antibody, DENN domain-containing protein 2B antibody, DENN/MADD domain containing 2B antibody, HeLa tumor suppression 1 antibody, HTS1 antibody, p126 antibody, ST 5 antibody, ST5 antibody, ST5_HUMAN antibody, Suppression of tumorigenicity 5 antibody, Suppression of tumorigenicity 5 protein antibody

UniProt: P78524