HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 33-315) antibody

Catalog No. ABIN7171185

The Rabbit Polyclonal anti-HERV-FRD Provirus Ancestral Env Polyprotein antibody is suitable to detect HERV-FRD Provirus Ancestral Env Polyprotein in samples from Human. It has been validated for WB and ELISA.

Quick Overview for HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 33-315) antibody (ABIN7171185)

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 33-315

Purpose: ERVFRD-1 Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Syncytin-2 protein (33-315aa)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Alternative Name: ERVFRD-1

Background:

Background: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732).

Aliases: Syncytin-2 (Endogenous retrovirus group FRD member 1) (Envelope polyprotein) (HERV-FRD) (HERV-FRD_6p24.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU), Transmembrane protein (TM)], ERVFRD-1, ERVFRDE1

UniProt: P60508