RIC8A antibody (AA 362-531)
Quick Overview for RIC8A antibody (AA 362-531) (ABIN7171203)
Target
See all RIC8A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 362-531
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Synembryn-A protein (362-531AA)
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Isotype
- IgG
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anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 462-534) antibody
RIC8A Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1H6 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyRIC8A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 362-531) antibodyRIC8A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) antibodyRIC8A Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 244-272) antibodyRIC8A Reactivity: Human WB Host: Rabbit Polyclonal RB37066 unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (C-Term) antibodyVerified RIC8A Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (AA 143-192) antibodyRIC8A Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A) (N-Term) antibodyRIC8A Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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Alternative Name
- RIC8A
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Background
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Background: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
Aliases: MGC104517 antibody, MGC131931 antibody, MGC148073 antibody, MGC148074 antibody, Protein Ric-8A antibody, resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody, RIC8 antibody, RIC8A antibody, RIC8A_HUMAN antibody, Synembryn-A antibody
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UniProt
- Q9NPQ8
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
Target
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