THOC6 antibody (AA 56-315) (HRP)

Catalog No. ABIN7172066

This Rabbit Polyclonal antibody specifically detects THOC6 in ELISA. It exhibits reactivity toward Human.

Quick Overview for THOC6 antibody (AA 56-315) (HRP) (ABIN7172066)

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THOC6 antibody is conjugated to HRP

Application: ELISA

Product Details anti-THOC6 Antibody (HRP)

Binding Specificity: AA 56-315

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human THO complex subunit 6 homolog protein (56-315AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for THOC6

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Alternative Name: THOC6

Background:

Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

Aliases: THOC6 antibody, WDR58 antibody, PSEC0006 antibody, THO complex subunit 6 homolog antibody, Functional spliceosome-associated protein 35 antibody, fSAP35 antibody, WD repeat-containing protein 58 antibody

UniProt: Q86W42