TFE3 antibody (AA 1-110) (FITC)
Quick Overview for TFE3 antibody (AA 1-110) (FITC) (ABIN7172532)
Target
See all TFE3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-110
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Transcription factor E3 protein (1-110AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TFE3 (Transcription Factor E3 (TFE3))
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Alternative Name
- TFE3
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Background
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Background: Transcription factor that specifically recognizes and binds E-box sequences (5\'-CANNTG-3\'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Aliases: bHLH e33 antibody, bHLHe33 antibody, Class E basic helix-loop-helix protein 33 antibody, RCCP 2 antibody, RCCP2 antibody, RCCX1 antibody, Renal cell carcinoma, papillary antibody, Tcfe 3 antibody, Tcfe3 antibody, TFE 3 antibody, Tfe3 antibody, TFE3_HUMAN antibody, TFEA antibody, Transcription factor binding to IGHM enhancer 3 antibody, Transcription factor E family, member A antibody, Transcription factor E3 antibody, Transcription factor for IgH enhancer antibody, Transcription factor for immunoglobulin heavy chain enhancer 3 antibody
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UniProt
- P19532
Target
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