TLE4 antibody (AA 284-394) (Biotin)

Catalog No. ABIN7172792

This Rabbit Polyclonal antibody specifically detects TLE4 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TLE4 antibody (AA 284-394) (Biotin) (ABIN7172792)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE4 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TLE4 Antibody (Biotin)

Binding Specificity: AA 284-394

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transducin-like enhancer protein 4 protein (284-394AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Alternative Name: TLE4

Background:

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).

Aliases: TLE4 antibody, GRG4 antibody, KIAA1261 antibody, Transducin-like enhancer protein 4 antibody, Grg-4 antibody, Groucho-related protein 4 antibody

UniProt: Q04727

Pathways: WNT Signaling