ANGPTL4 antibody (AA 26-406) (HRP)

Catalog No. ABIN7173339

The Rabbit Polyclonal anti-ANGPTL4 antibody has been validated for ELISA. It is suitable to detect ANGPTL4 in samples from Human.

Quick Overview for ANGPTL4 antibody (AA 26-406) (HRP) (ABIN7173339)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is conjugated to HRP

Application: ELISA

Product Details anti-ANGPTL4 Antibody (HRP)

Binding Specificity: AA 26-406

Cross-Reactivity: Human

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Trefoil factor 3 protein (26-406AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4

Background:

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).

Aliases: Angiopoietin like 4 antibody, Angiopoietin related protein 4 antibody, Angiopoietin-like protein 4 antibody, Angiopoietin-related protein 4 antibody, ANGL4_HUMAN antibody, ANGPT L2 antibody, ANGPT L4 antibody, ANGPTL2 antibody, Angptl4 antibody, ARP4 antibody, Fasting induced adipose factor antibody, FIAF antibody, HARP antibody, Hepatic angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin-related protein antibody, HFARP antibody, NL2 antibody, Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody, PGAR antibody, pp1158 antibody, PPARG angiopoietin related protein antibody, PSEC0166 antibody, TGQTL antibody, UNQ171 antibody, Weakly similar to angiopoietin 1 [H.sapiens] antibody

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha