TULP3 antibody (AA 1-260)
Quick Overview for TULP3 antibody (AA 1-260) (ABIN7173639)
Target
See all TULP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-260
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Tubby-related protein 3 protein (1-260AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TULP3 (Tubby Like Protein 3 (TULP3))
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Alternative Name
- TULP3
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Background
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Background: Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.
Aliases: MGC45295 antibody, Tubby like protein 3 antibody, Tubby related protein 3 antibody, Tubby-like protein 3 antibody, Tubby-related protein 3 antibody, TUBL 3 antibody, TUBL3 antibody, TULP 3 antibody, TULP3 antibody, TULP3_HUMAN antibody
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UniProt
- O75386
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
Target
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