TUSC3 antibody (AA 42-196) (Biotin)

Catalog No. ABIN7173931

This anti-TUSC3 antibody is a Rabbit Polyclonal antibody detecting TUSC3 in ELISA. Suitable for Human.

Quick Overview for TUSC3 antibody (AA 42-196) (Biotin) (ABIN7173931)

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUSC3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TUSC3 Antibody (Biotin)

Binding Specificity: AA 42-196

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tumor suppressor candidate 3 protein (42-196AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TUSC3

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Alternative Name: TUSC3

Background:

Background: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Aliases: TUSC3 antibody, N33Tumor suppressor candidate 3 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3 antibody, Oligosaccharyl transferase subunit TUSC3 antibody, Magnesium uptake/transporter TUSC3 antibody, Protein N33 antibody

UniProt: Q13454

Pathways: Cell RedoxHomeostasis