DIO2 antibody (AA 74-222)

Catalog No. ABIN7173972

Product Details anti-DIO2 Antibody

Target: DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))

Binding Specificity: AA 74-222

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Type II iodothyronine deiodinase protein (74-222AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DIO2

Target: DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))

Alternative Name: DIO2 (DIO2 Products)

Background:

Background: Responsible for the deiodination of T4 (3,5,3\\\',5\\\'-tetraiodothyronine) into T3 (3,5,3\\\'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.

Aliases: 5DII antibody, D2 antibody, Deiodinase, iodothyronine, type II antibody, DIO2 antibody, DIOII antibody, EC 1.97.1.10 antibody, IOD2_HUMAN antibody, ITDI2 antibody, SelY antibody, Thyroxine deiodinase, type II antibody, TXDI2 antibody, Type 2 DI antibody, Type 2 iodothyronine deiodinase antibody, Type II 5' deiodinase antibody, Type II iodothyronine deiodinase antibody, Type-II 5''-deiodinase antibody

UniProt: Q92813

Pathways: Hormone Transport, Hormone Activity