DIO2 antibody (AA 165-191)

Catalog No. ABIN5531011

The Rabbit Polyclonal anti-DIO2 antibody (ABIN5531011) specifically detects DIO2 in WB, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for DIO2 antibody (AA 165-191) (ABIN5531011)

Target: DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-DIO2 Antibody

Binding Specificity: AA 165-191

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DIO2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DIO2

Target: DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))

Alternative Name: DIO2

Background: DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3).

Molecular Weight: 31 kDa

Gene ID: 1734

UniProt: Q92813

Pathways: Hormone Transport, Hormone Activity