PTPN12 antibody (AA 539-714)

Catalog No. ABIN7174089

The Rabbit Polyclonal anti-PTPN12 antibody has been validated for WB, ELISA and IHC. It is suitable to detect PTPN12 in samples from Human.

Quick Overview for PTPN12 antibody (AA 539-714) (ABIN7174089)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PTPN12 Antibody

Binding Specificity: AA 539-714

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Tyrosine-protein phosphatase non-receptor type 12 protein (539-714AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Alternative Name: PTPN12

Background:

Background: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:18559503). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 (PubMed:17329398, PubMed:27134172). Selectively dephosphorylates ERBB2 phosphorylated at \\\'Tyr-1112\\\', \\\'Tyr-1196\\\', and/or \\\'Tyr-1248\\\' (PubMed:27134172).

Aliases: Protein tyrosine phosphatase G1 antibody, Protein tyrosine phosphatase non receptor type 12 antibody, Protein-tyrosine phosphatase G1 antibody, PTN12_HUMAN antibody, PTP PEST antibody, PTP-PEST antibody, PTPG1 antibody, Ptpn12 antibody, Tyrosine protein phosphatase non receptor type 12 antibody, Tyrosine-protein phosphatase non-receptor type 12 antibody

UniProt: Q05209