UBIAD1 antibody (AA 1-82) (Biotin)

Catalog No. ABIN7174221

The Rabbit Polyclonal anti-UBIAD1 antibody has been validated for ELISA. It is suitable to detect UBIAD1 in samples from Human.

Quick Overview for UBIAD1 antibody (AA 1-82) (Biotin) (ABIN7174221)

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBIAD1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-UBIAD1 Antibody (Biotin)

Binding Specificity: AA 1-82

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human UbiA prenyltransferase domain-containing protein 1 protein (1-82AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBIAD1

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Alternative Name: UBIAD1

Background:

Background: Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione, K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.

Aliases: RP4-796F18.1 antibody, SCCD antibody, TERE 1 antibody, tere1 antibody, Transitional epithelia response protein antibody, Transitional epithelial response protein 1 antibody, UbiA prenyltransferase domain containing 1 antibody, UbiA prenyltransferase domain containing protein 1 antibody, UbiA prenyltransferase domain-containing protein 1 antibody, UBIA1_HUMAN antibody, UBIAD 1 antibody, Ubiad1 antibody

UniProt: Q9Y5Z9