UFD1L antibody (AA 1-307)

Catalog No. ABIN7174388

This Rabbit Polyclonal antibody specifically detects UFD1L in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for UFD1L antibody (AA 1-307) (ABIN7174388)

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UFD1L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-UFD1L Antibody

Binding Specificity: AA 1-307

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Alternative Name: UFD1

Background:

Background: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.

Aliases: UB fusion protein 1 antibody, Ubiquitin fusion degradation 1 like (yeast) antibody, Ubiquitin fusion degradation 1 like antibody, Ubiquitin fusion degradation protein 1 homolog antibody, UFD1 antibody, UFD1_HUMAN antibody, UFD1L antibody

UniProt: Q92890