YOD1 antibody (AA 1-44)

Catalog No. ABIN7174389

The Rabbit Polyclonal anti-YOD1 antibody has been validated for ELISA and IF. It is suitable to detect YOD1 in samples from Human.

Quick Overview for YOD1 antibody (AA 1-44) (ABIN7174389)

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-YOD1 Antibody

Binding Specificity: AA 1-44

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin thioesterase OTU1 protein (1-44AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1

Background:

Background: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP\\\'s axial channel. Mediates deubiquitination of \\\'Lys-27\\\'-, \\\'Lys-29\\\'- and \\\'Lys-33\\\'-linked polyubiquitin chains. Also able to hydrolyze \\\'Lys-11\\\'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.

Aliases: DUBA-8 antibody, DUBA8 antibody, HIN-7 antibody, HIV-1-induced protease 7 antibody, HsHIN7 antibody, OTU domain containing 2 antibody, OTU domain-containing protein 2 antibody, OTU1_HUMAN antibody, OTUD2 antibody, PRO0907 antibody, RP11-164O23.1 antibody, Ubiquitin thioesterase OTU1 antibody, yod1 antibody, YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) antibody, YOD1 OTU deubiquinating enzyme 1 homolog (yeast) antibody, YOD1 OTU deubiquinating enzyme 1, S. cerevisiae, homolog of antibody

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling