UBE2C antibody (AA 2-179) (HRP)

Catalog No. ABIN7174433

This Rabbit Polyclonal antibody specifically detects UBE2C in ELISA. It exhibits reactivity toward Human.

Quick Overview for UBE2C antibody (AA 2-179) (HRP) (ABIN7174433)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2C antibody is conjugated to HRP

Application: ELISA

Product Details anti-UBE2C Antibody (HRP)

Binding Specificity: AA 2-179

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 C protein (2-179AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Alternative Name: UBE2C

Background:

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \'Lys-11\'- and \'Lys-48\'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating \'Lys-11\'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Aliases: Cyclin selective ubiquitin carrier protein antibody, dJ447F3.2 antibody, Mitotic specific ubiquitin conjugating enzyme antibody, UB E2C antibody, UBCH 10 antibody, UbcH10 antibody, UBE 2C antibody, Ube2c antibody, UBE2C_HUMAN antibody, Ubiquitin carrier protein C antibody, Ubiquitin carrier protein E2 C antibody, Ubiquitin carrier protein E2C antibody, Ubiquitin conjugating enzyme E2 C antibody, Ubiquitin conjugating enzyme E2C antibody, Ubiquitin protein ligase C antibody, Ubiquitin-conjugating enzyme E2 C antibody, Ubiquitin-protein ligase C antibody

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway