MYO1E antibody (AA 62-189)

Catalog No. ABIN7174945

This anti-MYO1E antibody is a Rabbit Polyclonal antibody detecting MYO1E in IHC and ELISA. Suitable for Human.

Quick Overview for MYO1E antibody (AA 62-189) (ABIN7174945)

Target: MYO1E (Myosin IE (MYO1E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO1E antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-MYO1E Antibody

Binding Specificity: AA 62-189

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-Ie protein (62-189AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYO1E

Target: MYO1E (Myosin IE (MYO1E))

Alternative Name: MYO1E

Background:

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.

Aliases: FSGS6 antibody, HuncM-IC antibody, MYO1C antibody, Myo1e antibody, MYO1E variant protein antibody, MYO1E_HUMAN antibody, Myosin heavy chain myr 3 antibody, Myosin IC, formerly antibody, Myosin IE antibody, Myosin-Ic antibody, Myr 3 antibody, Myr3 antibody, MYR5 antibody, Unconventional myosin 1E antibody, Unconventional myosin Ie antibody, Unconventional myosin-Ie antibody

UniProt: Q12965

Pathways: Platelet-derived growth Factor Receptor Signaling