Myosin X antibody (AA 1-97)

Catalog No. ABIN7174965

The Rabbit Polyclonal anti-Myosin X antibody has been validated for ELISA, IHC and IF. It is suitable to detect Myosin X in samples from Human.

Quick Overview for Myosin X antibody (AA 1-97) (ABIN7174965)

Target: Myosin X (MYO10)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin X antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Myosin X Antibody

Binding Specificity: AA 1-97

Purpose: MYO10 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Unconventional myosin-X protein (1-97AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Myosin X

Target: Myosin X (MYO10)

Alternative Name: MYO10

Background:

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts.

Aliases: AW048724 antibody, D15Ertd600e antibody, FLJ10639 antibody, FLJ21066 antibody, FLJ22268 antibody, FLJ43256 antibody, KIAA0799 antibody, MGC131988 antibody, mKIAA0799 antibody, MYO10 antibody, MYO10_HUMAN antibody, Myosin X antibody, Myosin-X antibody, OTTMUSP00000022066 antibody, Unconventional myosin 10 antibody, Unconventional myosin X antibody, Unconventional myosin-10 antibody

UniProt: Q9HD67