CCDC53 antibody (AA 1-194) (Biotin)

Catalog No. ABIN7175684

This Rabbit Polyclonal antibody specifically detects CCDC53 in ELISA. It exhibits reactivity toward Human.

Quick Overview for CCDC53 antibody (AA 1-194) (Biotin) (ABIN7175684)

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC53 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CCDC53 Antibody (Biotin)

Binding Specificity: AA 1-194

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human WASH complex subunit 3 protein (1-194AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCDC53

Target: CCDC53 (Coiled-Coil Domain Containing 53 (CCDC53))

Alternative Name: WASHC3

Background:

Background: Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).

Aliases: WASHC3 antibody, AD-016 antibody, CCDC53 antibody, CGI-116 antibody, x0009 antibody, WASH complex subunit 3 antibody, Coiled-coil domain-containing protein 53 antibody

UniProt: Q9Y3C0