MORG1 antibody (AA 64-315) (Biotin)

Catalog No. ABIN7175711

This Rabbit Polyclonal antibody specifically detects MORG1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for MORG1 antibody (AA 64-315) (Biotin) (ABIN7175711)

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MORG1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MORG1 Antibody (Biotin)

Binding Specificity: AA 64-315

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human WD repeat domain-containing protein 83 protein (64-315AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MORG1

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Alternative Name: WDR83

Background:

Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Aliases: MAPK organizer 1 antibody, MGC4238 antibody, Mitogen activated protein kinase organizer 1 antibody, Mitogen-activated protein kinase organizer 1 antibody, MORG 1 antibody, WD repeat domain-containing protein 83 antibody, wdr83 antibody, WDR83_HUMAN antibody

UniProt: Q9BRX9