WDR34 antibody (AA 1-210) (HRP)

Catalog No. ABIN7175741

This Rabbit Polyclonal antibody specifically detects WDR34 in ELISA. It exhibits reactivity toward Human.

Quick Overview for WDR34 antibody (AA 1-210) (HRP) (ABIN7175741)

Target: WDR34 (WD Repeat Domain 34 (WDR34))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR34 antibody is conjugated to HRP

Application: ELISA

Product Details anti-WDR34 Antibody (HRP)

Binding Specificity: AA 1-210

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human WD repeat-containing protein 34 protein (1-210AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WDR34

Target: WDR34 (WD Repeat Domain 34 (WDR34))

Alternative Name: WDR34

Background:

Background: Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at \\\'Thr-184\\\' and \\\'Thr-187\\\' upon Il-1 beta stimulation.

Aliases: bA216B9.3 antibody, DIC5 antibody, MGC20486 antibody, OTTHUMP00000022282 antibody, RP11 216B9.5 antibody, WD repeat containing protein 34 antibody, WD repeat domain 34 antibody, WD repeat-containing protein 34 antibody, WDR 34 antibody, Wdr34 antibody, WDR34_HUMAN antibody

UniProt: Q96EX3