WT1 antibody (AA 1-449)

Catalog No. ABIN7175818

This anti-WT1 antibody is a Rabbit Polyclonal antibody detecting WT1 in IHC and ELISA. Suitable for Human.

Quick Overview for WT1 antibody (AA 1-449) (ABIN7175818)

Target: WT1 (Wilms Tumor 1 (WT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-WT1 Antibody

Binding Specificity: AA 1-449

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Wilms tumor protein (1-449AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: WT1

Background:

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5\'-CGCCCCCGC-3\'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Aliases: WIT 2 antibody, WT 1 antibody, AWT1 antibody, FWT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, Wilms tumor 1 antibody, Wilms Tumor antibody, Wilms tumor protein antibody, Wilms' tumor gene antibody, Wilms' tumor protein antibody, WIT2 antibody, WT antibody, WT1 antibody, WT1_HUMAN antibody, WT33 antibody

UniProt: P19544

Pathways: Tube Formation