Moloney Murine Leukemia Virus Gag (AA 216-478) antibody (HRP)

Catalog No. ABIN7176878

This Rabbit Polyclonal antibody specifically detects in ELISA. It exhibits reactivity toward Moloney Murine Leukemia Virus (MoMuLV).

Quick Overview for Moloney Murine Leukemia Virus Gag (AA 216-478) antibody (HRP) (ABIN7176878)

Target: Moloney Murine Leukemia Virus Gag

Reactivity: Moloney Murine Leukemia Virus (MoMuLV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Product Details

Binding Specificity: AA 216-478

Purpose: gag Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Moloney Murine Leukemia Virus Gag

Background:

Background: Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5\\\'-end of the genome. This binding is dependent on genome dimerization.

Aliases: gag antibody, Gag polyprotein antibody, Pr65gag antibody, Core polyprotein) [Cleaved into: Matrix protein p15 antibody, MA), RNA-binding phosphoprotein p12 antibody, pp12), Capsid protein p30 antibody, CA), Nucleocapsid protein p10-Gag antibody, NC-gag)] antibody

UniProt: P03332