SAMHD1 antibody (AA 426-657)

Catalog No. ABIN7177149

The Rabbit Polyclonal anti-SAMHD1 antibody has been validated for WB and ELISA. It is suitable to detect SAMHD1 in samples from Mouse.

Quick Overview for SAMHD1 antibody (AA 426-657) (ABIN7177149)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SAMHD1 Antibody

Binding Specificity: AA 426-657

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (426-657AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: Samhd1

Background:

Background: Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling (By similarity).

Aliases: Samhd1 antibody, Mg21 antibody, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody, dNTPase antibody, EC 3.1.5.- antibody, Interferon-gamma-inducible protein Mg11 antibody, SAM domain and HD domain-containing protein 1 antibody, mSAMHD1 antibody

UniProt: Q60710