Frataxin antibody (AA 78-207) (FITC)
Quick Overview for Frataxin antibody (AA 78-207) (FITC) (ABIN7177207)
Target
See all Frataxin (FXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
 - AA 78-207
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Cross-Reactivity
 - Mouse
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Purification
 - >95%, Protein G purified
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Immunogen
 - Recombinant Mouse Frataxin, mitochondrial protein (78-207AA)
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Isotype
 - IgG
 
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Buffer
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                        Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 
                                            
Preservative
 - ProClin
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Precaution of Use
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - -20 °C,-80 °C
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Storage Comment
 - Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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- Frataxin (FXN)
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Alternative Name
 - Fxn
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Background
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Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).
Aliases: Fxn antibody, FrdaFrataxin antibody, mitochondrial antibody, Fxn antibody, EC 1.16.3.1) [Cleaved into: Frataxin intermediate form, Frataxin mature form] antibody
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UniProt
 - O35943
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Pathways
 - Transition Metal Ion Homeostasis, Regulation of Cell Size
 
Target
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