Frataxin antibody (AA 78-207) (HRP)

Catalog No. ABIN7177208

This Rabbit Polyclonal antibody specifically detects Frataxin in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Frataxin antibody (AA 78-207) (HRP) (ABIN7177208)

Target: Frataxin (FXN)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Frataxin antibody is conjugated to HRP

Application: ELISA

Product Details anti-Frataxin Antibody (HRP)

Binding Specificity: AA 78-207

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Frataxin, mitochondrial protein (78-207AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: Fxn

Background:

Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).

Aliases: Fxn antibody, FrdaFrataxin antibody, mitochondrial antibody, Fxn antibody, EC 1.16.3.1) [Cleaved into: Frataxin intermediate form, Frataxin mature form] antibody

UniProt: O35943

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size