HAS2 antibody (AA 67-374)

Catalog No. ABIN7177301

This Rabbit Polyclonal antibody specifically detects HAS2 in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for HAS2 antibody (AA 67-374) (ABIN7177301)

Target: HAS2 (Hyaluronan Synthase 2 (HAS2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAS2 antibody is un-conjugated

Application: ELISA

Product Details anti-HAS2 Antibody

Binding Specificity: AA 67-374

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Hyaluronan synthase 2 protein (67-374AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HAS2

Target: HAS2 (Hyaluronan Synthase 2 (HAS2))

Alternative Name: Has2

Background:

Background: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.

Aliases: Has2 antibody, Hyaluronan synthase 2 antibody, EC 2.4.1.212 antibody, Hyaluronate synthase 2 antibody, Hyaluronic acid synthase 2 antibody, HA synthase 2 antibody

UniProt: P70312

Pathways: Glycosaminoglycan Metabolic Process