ITGAL antibody (AA 153-325) (Biotin)
Quick Overview for ITGAL antibody (AA 153-325) (Biotin) (ABIN7177322)
Target
See all ITGAL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 153-325
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Cross-Reactivity
- Mouse
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Mouse Integrin alpha-L protein (153-325AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ITGAL (Integrin alpha-L (ITGAL))
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Alternative Name
- Itgal
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Background
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Background: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Mice expressing a null mutation of the alpha-L subunit gene demonstrate impaired tumor rejection and impaired leukocytes recruitment.
Aliases: Itgal antibody, Lfa-1 antibody, Ly-15Integrin alpha-L antibody, CD11 antigen-like family member A antibody, Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody, LFA-1A antibody, Leukocyte function-associated molecule 1 alpha chain antibody, Lymphocyte antigen 15 antibody, Ly-15 antibody, CD antigen CD11a antibody
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UniProt
- P24063
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
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