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LOXL2 antibody (AA 26-776) (Biotin)

This Rabbit Polyclonal antibody specifically detects LOXL2 in ELISA. It exhibits reactivity toward Mouse.
Catalog No. ABIN7177406

Quick Overview for LOXL2 antibody (AA 26-776) (Biotin) (ABIN7177406)

Target

See all LOXL2 Antibodies
LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Reactivity

  • 64
  • 33
  • 32
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Mouse

Host

  • 87
  • 6
Rabbit

Clonality

  • 77
  • 16
Polyclonal

Conjugate

  • 53
  • 12
  • 11
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This LOXL2 antibody is conjugated to Biotin

Application

  • 68
  • 36
  • 29
  • 21
  • 14
  • 7
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA
  • Binding Specificity

    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-776

    Cross-Reactivity

    Mouse

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

    Alternative Name

    Loxl2

    Background

    Background: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

    Aliases: Loxl2Lysyl oxidase homolog 2 antibody, EC 1.4.3.13 antibody, Lysyl oxidase-like protein 2 antibody

    UniProt

    P58022

    Pathways

    Chromatin Binding
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