PDXP antibody (AA 1-292)

Catalog No. ABIN7177810

The Rabbit Polyclonal anti-PDXP antibody (ABIN7177810) specifically detects PDXP in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for PDXP antibody (AA 1-292) (ABIN7177810)

Target: PDXP (Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase (PDXP))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDXP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDXP Antibody

Binding Specificity: AA 1-292

Purpose: Pdxp Antibody

Cross-Reactivity: Rat

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Mouse Pyridoxal phosphate phosphatase protein (1-292AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDXP

Target: PDXP (Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase (PDXP))

Alternative Name: Pdxp

Background:

Background: Protein serine phosphatase that dephosphorylates \\\'Ser-3\\\' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis (By similarity). Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5\\\'-phosphate (PLP), pyridoxine 5\\\'-phosphate (PMP) and pyridoxine 5\\\'-phosphate (PNP), with a highest activity with PLP followed by PNP.

Aliases: Pdxp antibody, Cin antibody, Plp antibody, Plpp antibody, Pyridoxal phosphate phosphatase antibody, PLP phosphatase antibody, EC 3.1.3.3 antibody, EC 3.1.3.74 antibody, Chronophin antibody

UniProt: P60487