CD163 antibody (AA 86-365)

Catalog No. ABIN7177826

This Rabbit Polyclonal antibody specifically detects CD163 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for CD163 antibody (AA 86-365) (ABIN7177826)

Target: CD163

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD163 Antibody

Binding Specificity: AA 86-365

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD163

Target: CD163

Alternative Name: Cd163

Background:

Background: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).

Aliases: Cd163 antibody, M130Scavenger receptor cysteine-rich type 1 protein M130 antibody, CD antigen CD163) [Cleaved into: Soluble CD163 antibody, sCD163)] antibody

UniProt: Q2VLH6