RANKL antibody (AA 73-306)

Catalog No. ABIN7177979

Product Details anti-RANKL Antibody

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Binding Specificity: AA 73-306

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANKL antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Tumor necrosis factor ligand superfamily member 11 protein (73-306AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RANKL

Target: RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))

Alternative Name: Tnfsf11 (TNFSF11 Products)

Background:

Background: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Aliases: Tnfsf11 antibody, Opgl antibody, Rankl antibody, Trance antibody, Tumor necrosis factor ligand superfamily member 11 antibody, Osteoclast differentiation factor antibody, ODF antibody, Osteoprotegerin ligand antibody, OPGL antibody, Receptor activator of nuclear factor kappa-B ligand antibody, RANKL antibody, TNF-related activation-induced cytokine antibody, TRANCE antibody, CD antigen CD254) [Cleaved into: Tumor necrosis factor ligand superfamily member 11 antibody, membrane form, Tumor necrosis factor ligand superfamily member 11 antibody, soluble form] antibody

UniProt: O35235

Pathways: NF-kappaB Signaling