PDSS1 antibody (AA 1-183) (Biotin)

Catalog No. ABIN7178024

This Rabbit Polyclonal antibody specifically detects PDSS1 in ELISA. It exhibits reactivity toward Mycobacterium smegmatis.

Quick Overview for PDSS1 antibody (AA 1-183) (Biotin) (ABIN7178024)

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Reactivity: Mycobacterium smegmatis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDSS1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PDSS1 Antibody (Biotin)

Binding Specificity: AA 1-183

Cross-Reactivity: Mycobacterium smegmatis

Purification: >95%, Protein G purified

Immunogen: Recombinant Mycobacterium smegmatis DNA protection during starvation protein (1-183AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDSS1

Target: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Alternative Name: dps

Background:

Background: Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage.

Aliases: dpsDNA protection during starvation protein antibody, EC 1.16.-.- antibody

UniProt: P0C558