CD8 alpha antibody (FITC)

Catalog No. ABIN7178436

The Rat Monoclonal anti-CD8 alpha antibody has been validated for FACS, IF and ELISA. It is suitable to detect CD8 alpha in samples from Mouse.

Quick Overview for CD8 alpha antibody (FITC) (ABIN7178436)

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8 alpha antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Product Details anti-CD8 alpha Antibody (FITC)

Cross-Reactivity: Mouse

Purification: Affinity purified

Immunogen: Recombinant Protein

Isotype: IgG2b

Application Details

Application Notes: Recommended dilution:IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD8 alpha

Target: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name: CD8A

Background:

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: N/A

UniProt: P01732

Pathways: TCR Signaling