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ITGAL antibody (PE)

ITGAL Reactivity: Human FACS, ELISA, IF Host: Mouse Monoclonal PE
Catalog No. ABIN7178494
  • Target See all ITGAL Antibodies
    ITGAL (Integrin alpha-L (ITGAL))
    Reactivity
    • 132
    • 65
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 103
    • 53
    • 43
    • 1
    Mouse
    Clonality
    • 156
    • 43
    • 1
    Monoclonal
    Conjugate
    • 73
    • 27
    • 23
    • 17
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAL antibody is conjugated to PE
    Application
    • 144
    • 42
    • 36
    • 32
    • 28
    • 28
    • 22
    • 17
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    Affinity purified
    Immunogen
    Recombinant Protein
    Isotype
    IgG1, IgG1 kappa
    Top Product
    Discover our top product ITGAL Primary Antibody
  • Application Notes
    Recommended dilution:IF:1:100-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ITGAL (Integrin alpha-L (ITGAL))
    Alternative Name
    ITGAL (ITGAL Products)
    Background

    Background: 4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate.1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16:479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99.

    Aliases: N/A

    UniProt
    P20701
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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