Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PRNP antibody (AA 29-231) (Biotin)

The Rabbit Polyclonal anti-PRNP antibody has been validated for ELISA. It is suitable to detect PRNP in samples from Rat.
Catalog No. ABIN7178934

Quick Overview for PRNP antibody (AA 29-231) (Biotin) (ABIN7178934)

Target

See all PRNP Antibodies
PRNP (Prion Protein (PRNP))

Reactivity

  • 95
  • 35
  • 35
  • 13
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Rat

Host

  • 90
  • 20
  • 3
  • 2
  • 1
Rabbit

Clonality

  • 81
  • 35
Polyclonal

Conjugate

  • 58
  • 6
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PRNP antibody is conjugated to Biotin

Application

  • 63
  • 34
  • 27
  • 26
  • 25
  • 15
  • 12
  • 11
  • 11
  • 7
  • 6
  • 3
  • 1
  • 1
ELISA
  • Binding Specificity

    • 15
    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-231

    Cross-Reactivity

    Rat

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Rat Major prion protein (29-231AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    PRNP (Prion Protein (PRNP))

    Alternative Name

    Prnp

    Background

    Background: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.

    Aliases: Prnp antibody, Prn antibody, Prp antibody, Major prion protein antibody, PrP antibody, CD antigen CD230 antibody

    UniProt

    P13852

    Pathways

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
You are here:
Chat with us!