Rotavirus A Intermediate Capsid Protein VP6 (AA 1-397) antibody (Biotin)

Catalog No. ABIN7179162

Product Details

Target: Rotavirus A Intermediate Capsid Protein VP6

Binding Specificity: AA 1-397

Reactivity: Rotavirus A

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Cross-Reactivity: Rotavirus A

Purification: >95%, Protein G purified

Immunogen: Recombinant Rotavirus A Intermediate capsid protein VP6 protein (1-397AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Rotavirus A Intermediate Capsid Protein VP6

Alternative Name: Intermediate capsid protein VP6

Synonyms: Intermediate capsid protein VP6 antibody, LOC7011372 antibody

Target Type: Viral Protein

Background:

Background: Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nacent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.

Aliases: Intermediate capsid protein VP6 antibody

UniProt: P04509