Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) antibody
The Rabbit Polyclonal anti-Streptococcal Pyrogenic Exotoxin B antibody (ABIN7179505) specifically detects Streptococcal Pyrogenic Exotoxin B in ELISA and WB.
The antibody is reactive with Streptococcus pyogenes samples.
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Catalog No. ABIN7179505
$394.68
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Quick Overview for Streptococcal Pyrogenic Exotoxin B (SPEB) (AA 146-398) antibody (ABIN7179505)
Target
See all Streptococcal Pyrogenic Exotoxin B (SPEB) Antibodies
Streptococcal Pyrogenic Exotoxin B (SPEB)
Reactivity
Streptococcus pyogenes
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
ELISA, Western Blotting (WB)
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Binding Specificity
- AA 146-398
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Purpose
- speB Antibody
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Purification
- Protein G purified
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Purity
- >95 %
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Immunogen
- Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Streptococcal Pyrogenic Exotoxin B (SPEB)
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Alternative Name
- speB
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Background
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Background: Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).
Aliases: speB antibody, M28_Spy1721 antibody, Streptopain antibody, EC 3.4.22.10 antibody, Exotoxin type B antibody, SPE B antibody, Streptococcal cysteine proteinase antibody, Streptococcus peptidase A antibody, SPP antibody
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UniProt
- Q48R29
Target
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