Integrin beta 4 antibody (Tyr1510)

Catalog No. ABIN7180035

The Rabbit Polyclonal anti-Integrin beta 4 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Integrin beta 4 in samples from Human.

Quick Overview for Integrin beta 4 antibody (Tyr1510) (ABIN7180035)

Target: Integrin beta 4 (ITGB4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Integrin beta 4 Antibody

Binding Specificity: Tyr1510

Cross-Reactivity: Human, Mouse, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Integrin beta 4

Target: Integrin beta 4 (ITGB4)

Alternative Name: ITGB4

Background:

Background: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.

Suzuki S., EMBO J. 9:757-763(1990).
Hogervorst F., EMBO J. 9:765-770(1990).
Tamura R.N., J. Cell Biol. 111:1593-1604(1990).

Aliases: CD 104 antibody, CD104 antibody, CD104 antigen antibody, gp150 antibody, Integrin beta 4 subunit antibody, Integrin beta-4 antibody, ITB4_HUMAN antibody, ITG B4 antibody, ITGB 4 antibody, Itgb4 antibody

UniProt: P16144

Pathways: Integrin Complex